Elevated cerebellar glucose metabolism in microvascular white matter disease: normal aging and Alzheimer's disease.

نویسندگان

  • A Klinger
  • M J de Leon
  • A E George
  • J D Miller
  • A P Wolf
چکیده

Young normal, elderly, and clinically diagnosed Alzheimer disease subjects who had undergone positron emission tomography (PET) and computed tomography (CT) examinations were studied to determine the effect of periventricular white matter lesions on cerebellar glucose metabolic rates. PET-determined cerebellar metabolic rates were elevated in subjects with periventricular white matter lesions. These results suggest the cautious use of cortical-to-cerebellar ratios in future PET or single-photon-emission CT (SPECT) studies.

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عنوان ژورنال:
  • Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

دوره 8 3  شماره 

صفحات  -

تاریخ انتشار 1988